High-Throughput Sequencing Technologies

High-throughput sequencing technologies.

The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years. Here, we discuss commonly used high-throughput sequencing platfo...

Algorithms for Next-Generation High-Throughput Sequencing Technologies

Algorithms for Next-Generation High-Throughput Sequencing Technologies

High throughput sequencing technologies — an algorithm for genome assembly

s 44 2010

SnapShot: High-Throughput Sequencing Applications

Ray: Simultaneous Assembly of Reads from a Mix of High-Throughput Sequencing Technologies

An accurate genome sequence of a desired species is now a pre-requisite for genome research. An important step in obtaining a high-quality genome sequence is to correctly assemble short reads into longer sequences accurately representing contiguous genomic regions. Current sequencing technologies continue to offer increases in throughput, and corresponding reductions in cost and time. Unfortuna...